Inflammatory Bowel Disease
(IBD; Crohn's Disease; Regional Enteritis; Ileitis; Granulomatous Ileocolitis; Ulcerative Colitis)
Definition
Inflammatory bowel disease (IBD) is the term used for a group of diseases and disorders that affect the intestinal tract. IBD causes the intestines to become inflamed and irritated. IBD is a lifelong illness that can be difficult to control.
IBD affects about 600,000 Americans every year. The two most common forms of of IBD are Crohn's disease , irritable bowel syndrome (IBS) , and ulcerative colitis .
There is no pharmacologic cure for IBD, but treatments can help control symptoms. While patients may temporarily recover and not experience any symptoms, recurring flare-ups are common.
Crohn's Disease

Causes
The exact causes of IBD are unknown, but some hypotheses include:
- Heredity—having another family member with IBD
- Contracting a germ or infection that affects the intestinal tract
- Compromised immune system or infection that affects the immune system
IBD is not a contagious infection, so it cannot be passed from person to person.
Risk Factors
A risk factor is something that increases your chance of getting a disease or condition.
The following factors increase your chance of developing IBD:
- Having a family member with IBD
- Being Caucasian or of northern European ancestry
- Jewish ancestry increases the risk of certain types of IBD
- Problems with the immune system
Symptoms
Symptoms depend on the type of IBD, but common symptoms may include:
- Abdominal pain and cramping
- Diarrhea
- Weight loss and loss of appetite
- Bleeding from the intestines
- Ulcers in the intestines
- Inflammation of the rectum
- Draining around the rectum
- Bloating or feeling of fullness
- Gas
- Bloody diarrhea
- Abdominal sounds (gurgling, etc.)
- Nausea and vomiting
- Joint pain
Diagnosis
Your doctor will ask about your symptoms and medical history, and perform a physical exam. Tests may include the following:
- Upper GI endoscopy —a thin, lighted tube inserted down the throat to examine the upper part of the intestines
- Colonoscopy —a thin, lighted tube inserted through the rectum and into the colon to examine the lining of the colon
- Barium enema —injection of fluid into the rectum that makes your colon show up on an x-ray so the doctor can see abnormal spots in your colon
- X-ray —a test that uses radiation to take a picture of structures inside the body, especially bones
-
Capsule endoscopy
—a wireless pill sized camera that you swallow
- It takes pictures of the small intestine as it passes through your intestines.
- Blood tests
- Stool culture
Colonoscopy

Treatment
Talk with your doctor about the best treatment plan for you. Treatment options include:
Lifestyle Changes
Eating a healthy diet, low in fats and rich in fruits, vegetables , can control IBD symptoms. Reducing fiber and dairy products in the diet is also recommended.
Reducing stress and getting plenty of rest can also reduce symptoms and flare-ups.
Medications
Most medications for IBD focus on reducing the inflammation that causes symptoms. Medications include:
- Anti-inflammatory drugs
- Corticosteroids
- Immune system suppressors
- Antibiotics to kill germs in the intestinal tract
- Antidiarrheals
- Laxatives
- Pain relievers
Surgery
While surgery is not helpful for all types of IBD, surgery to remove the colon is an option for patients who suffer from very severe ulcerative colitis.
RESOURCES:
American Academy of Family Physicians
http://www.aafp.org/
Nemours Foundation
http://www.kidshealth.org/
CANADIAN RESOURCES:
Canadian Family Physician
http://www.cfpc.ca/cfp/
Health Canada
http://www.hc-sc.gc.ca/
References:
The references below are cited on the following website:
American Gastroenterological Association website. Available at:
http://www.gastro.org/wmspage.cfm?parm1=851
. Accessed June 25, 2007.
Brandt LJ, Steiner-Grossman P, eds.
Treating IBD: A Patient’s Guide to the Medical and Surgical Management of Inflammatory Bowel Disease
. New York: Raven Press;1989.
Steiner-Grossman P, Banks PA, Present DH, eds.
The New People Not Patients: A Source Book for Living with IBD
. Dubuque, Iowa: Kendall/Hunt Publishing Company;1992.
Botoman VA, Bonner GF, Botoman DA. Management of inflammatory bowel disease.1998;57(1). American Family Physician website. Available at: http://www.aafp.org/afp/980101ap/botoman.html Accessed June 27, 2007.
Crohn's disease. Medline Plus Medical Encyclopedia. US National Library of Medicine website. Available at: http://www.nlm.nih.gov/medlineplus/ency/article/000249.htm . Accessed June 27, 2007.
DynaMed website. Available at: http://dynamed102.ebscohost.com/Detail.aspx?style=1&docid=/dynamed/2ce4ecad72b93cc7852562b600120334 . Accessed June 25, 2007.
Inflammatory bowel disease. American Academy of Family Physicians website. Available at: http://familydoctor.org/online/famdocen/home/common/digestive/disorders/252.html . Accessed June 27, 2007.
Ulcerative colitis. Medline Plus Medical Encyclopedia. US National Library of Medicine website. Available at: http://www.nlm.nih.gov/medlineplus/ency/article/000250.htm . Accessed June 27, 2007.
Last reviewed November 2008 by Daus Mahnke, MD
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.
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