Definition
X-linked adrenoleukodystrophy (ALD) is a rare inherited genetic disorder. There have been 34 types of ALD described. X-linked ALD is the most common category. ALD results in degeneration of:
- Myelin sheath—fatty insulation covering on nerve fibers in the brain
- Adrenal gland and surrounding adrenal cortex—produces vital hormones
Myelin Sheath Around Nerve Fiber
There are six types of X-linked ALD:
- Childhood cerebral ALD
- Adolescent ALD
- Adrenomyeloneuropathy
- Adult cerebral ALD
- Adrenal insufficiency-only
- Symptomatic heterozygotes
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