Facebook Pixel

Overactive Bladder: Can Marijuana Potentially Treat It?

 
Rate This

First, a disclaimer. This blog post does not endorse the use of marijuana as it is illegal; however I recently read several studies of interest on this topic.

THC, tretrahydrocannabinol, is the major active ingredient in the marijuana and well known for inducing euphoria and relaxation, as well as sedation and drowsiness. It has been used for treating nerve pain, or neuropathic pain, cancer pain and even convulsions seen with multiple sclerosis.

AJA, Ajulemic acid, is the synthetic equivalent to THC, and is a strong pain reliever an anti-inflammatory but does not have the mind altering effects the THC has. In lab studies, it mimics many of the same properties as the popular anti-inflammatories known as NSAIDs, such a motrin or naproxen. In studies on neuropathic pain and volunteers, AJA did not cause dependency after withdrawal at the end of a one-week treatment period.

So, how would AJA potentially treat overactive bladder? A recent study on rats showed that AJA was able to suppress normal bladder activity and urinary frequency induced by bladder irritants. The researchers believe that AJA blocks the outgoing pain signal from the bladder by one of the receptors it and THC can bind to in the bladder. In the experiment, two different bladder irritants were administered to rats. Bladder pressure and contractions were measured. After injection of AJA, the bladder muscle contraction intervals and bladder pressures were blocked reversing the effect of the irritants.

So what does this mean? AJA is a promising compound that can have potentially broad application in treating the pain and overactivity symptoms that occur in many bladder conditions such as overactive bladder, interstitial cystitis, and perhaps even the bladder pain after surgery or urinary tract infections. One wonders if it many also be effective in not only treating the pain or symptoms after they occur but also given before to prevent them as well. Hmm….

http://www.femaleurologyaz.blogspot.com

Add a Comment25 Comments

EmpowHER Guest
Anonymous (reply to Anonymous)

In response: the doc is saying that marijuana helps overactive bladder, not a weak bladder like you have. Apparently, the marijuana has dulled your brain and you didn't catch that point in his article. Maybe your marijuana use lead to a weak bladder

January 16, 2010 - 6:17am
EmpowHER Guest
Anonymous

I have been smoking marijuana for 30 years and I have a bad case of overactive bladder, the only way I found to help is Enablex.

December 27, 2009 - 7:08am
EmpowHER Guest
Anonymous (reply to Anonymous)

I think the point you demonstrate is that chronic early use of marijuana "dull" any response you have to it for medicinal purposes. The OAB developed later in the background of your usage of marijuana, showing perhaps that your OAB developed via other mechanisms

January 16, 2010 - 6:15am
EmpowHER Guest
Anonymous

Of course pharmas are going to try and create something out of it, as they can't patent, or regulate something that grows naturally and plentiful. It's all in the big bucks for them, money runs politics and big corporations..unfortunately, the comman person is too ignorant to realize this..

December 25, 2009 - 1:32am

I use the substance mentioned here in my pain control regimen. I am in pain each day. There are easier days and more challenging ones. I also use a C II pain reliever and one NSAID. I have been getting bimonthly massages but have canceled my last scheduled appointment because they only help with the pain for a day.

Back to the subject. (You have to watch me. lol) I live in Omaha, Nebraska. The penalty for posession of less than one ounce of marijuana is a ticket for a $200. I don't take it out of the house so that won't be a problem for me.

Decriminalize possession but do not legalize marijuana. The government will charge big bucks for it. I also think they would require a "drug stamp" here. Like tags for your car they would require us to pay a fee every year just for using the marijuana.

I'm yammering. I'm so glad to be here. They have so much information.

Merry Christmas

December 24, 2009 - 11:19am
EmpowHER Guest
Anonymous

I am a chronic marijuana user, and am also prescirbed marinol for nausea and apetite problems. I also have a overactive bladder and have found no correlation in my marijuana use to my bladder getting better. I generally smoke multiple times throughout the day to help my body, and wish it would also help with bladder problems unfortunately have not found anything of this sort to work.

December 11, 2009 - 10:14pm
EmpowHER Guest
Anonymous

I agree with the posters saying that this helps the marijuana legalization cause. However, why not just use the real thing, rather than use some synthetic? I know, working conditions and all of that, but just think of this. Big Pharma has damaged the world in a rather sever fashion. Example: Opium = natrual substance (yes, it's addictive, but bear with me). Opium + adulteration = Morphine (Also VERY addictive). Morphine + Big Pharma (Bayer, to be exact) = Heroin!! That's right, the world scourge of addiction and destruction was created by BAYER. Worse, it was created as a way to wean people off of MORPHINE ADDICTION! Now, guess what. Big Pharma creates Methadone. Also highly addictive, and used as a way to wean people off of HEROINE! Good grief! Here's the point. If Marijuana works, then use it! If Big Pharma get's a hold of it, then they'll most likely create a monster that will add to way more problems that it solves. They only want to make a pill out of it so they can make even more money, and keep the rest of us ignant Amurikens in the dark about a natural weed that can do the same thing.

December 8, 2009 - 12:23pm
EmpowHER Guest
Anonymous (reply to Anonymous)

It's not Americans that truly support Big Pharma, it's our corrupt politicians and the lobbyists in their pockets. It's the same reason, even though it's very unhealthy, that dairy and animal farming are supported in this country. Us Americans constantly strive for change, but due to the overwhelming support of religious thoughts, corporations that preserve only their wealth, and politicians that are only concerned with status, prevent actual change from happening. Look at what is going on at Capitol Hill now, a public health option that has a majority support is constantly being stopped. Why? Because of religious institutions that are afraid of social programs, even though they still support Medicare, but a more socialized nation would help to bring an end to religious power and subjugation. That's the only reason change is stopped in this country.

The people with the least amount of proof, with the least amount of facts. with the smallest amount of compassion for their fellow Americans are the ones that get all the attention. If Glenn Beck was standing on a soap-box at a street corner, which his show is exactly that, he would be regarded as a crazy street-preacher. Instead he gets air time. Sarah Palin, who is about as worldly and intelligent as Plymouth Rock, only gets face time because she's mildly attractive and helps the Republican (and religious) demographic to be more appealing. Same applies to all the other talking heads out there. There is a reason that the most honest and trustworthy news anchor works at Comedy Central, none of the 24-hour news networks care about the truth, they just seek to fill the time that they have to air. Which is why we are inundated with celebrity deaths and dramas and news that's better left at local levels, news that only matters to a local stage that is.

The only way this country will ever be fixed, and actual have equal rights, is to shut down the religious fundamentalists and make the news networks accountable for their misinformation and petty lies. Religious people, as is the nature of their beliefs, are hardcore bigots. That bigotry, often times hidden behind religious dogma, is destroying this country and is alienating us from the rest of the world. Especially since so many christians think that: a) we are a christian nation, forgetting that we are actually secular. And b) they act disgusted whenever the words "muslim" or "atheist" pop up. They treat us how they claim they are treated. Hypocrisy knows no bounds, especially when religion is involved. There are those of us out there trying to help, trying to make a difference but our voices and words get snuffed because they disagree with what the religious peoples agenda in this country are. Truth and facts get left at the wayside, while hyperbole and rhetoric are spread like wildfires. That's what truly needs to be stopped. Free speech shouldn't apply to actively spreading lies that seek to only divide and inflame, spread fear and hate, and treat Americans as ignorant fodder.

December 8, 2009 - 1:55pm
EmpowHER Guest
Anonymous

This information, when tacked onto all the other marijuana benefits, help to push towards this country not being so misinformed about marijuana. A a woman's empowerment page there are some other things about marijuana you should know. Smoking marijuana, much like smoking any substance, has been shown to increase the chances of developing cancer. However marijuana has been shown to fight brain cancer by causing autophagy in the cancerous tumor cells. It has also been shown to help combat Alzheimer's disease as well as helping to prevent the spread of Breast Cancer. These findings, on top of many others, help to show that marijuana being illegal is pointless and insipid. Smoking it may be detrimental to your health but as I said all smoking is; smoke doesn't belong in our lungs period. Thankfully though there are many other ways of experiencing the wonderful benefits of marijuana. It's not water soluable but if mixed with a fat (like butter) you can make THC butter. Which you can then use to bake or cook healthy, mildly-psychoactive, foods.

A lot of the information out there about marijuana is incredibly misleading and at times just wrong. You can't overdose on marijuana, it's physically impossible to do so. In order to die from using marijuana you'd have to smoke a half-ton of it in ten minutes; as I said physically impossible. In fact no single death, ever, has been directly linked to marijuana usage. That's not to say no one has ever died from it's use, it's just never been solely marijuana's fault. Aspirin is more deadly than marijuana. As is caffeine, sugar, fats, meat, alcohol, cigarettes, Prozac,Paxil, Wellbutrin, Tylenol, lithium, Dramamine, DXM (cough medicine), and scores of others that are legal and can kill you. In fact it's illegality is only a result of years of misinformation and lobbying from cotton farmers, paper manufacturers and pharmaceutical companies. The marijuana, and hemp, plants are verstile and have thousands of uses. Hemp can be used to make so many products and it's far better for the environment and it's easier to grow.

All of the positive benefits of marijuana are greatly ignored and false-truths are the only reason it's not legal. It is not a gateway drug, it's addictive properties are scant and it does not turn you a raving lunatic (1933's Reefer Madness was just false propaganda. The only reason that marijuana is illegal is because people don't know the actual facts about this "drug"; which has been used for thousands of years. Recently they found marijuana and a pipe that were 1500 years old. And that marijuana was more potent than what we have today.

Another interesting fact is that of all the drugs people take, marijuana is the only one that has it's own receptor in the brain. All the other drugs, like opiates and barbiturates, mimic our receptors to achieve there effects. Marijuana doesn't, our bodies have designed a system to make it's usage even easier and safer. It has also been proven, by a many-years study Britain, that marijuana's effects on memory are greatly exaggerated. After 20 years they found that the only people that suffered memory issues, and they were minor at best, were the ones that were daily smokers for the duration of the study. The people that smoked socially or intermittently showed almost no signs of memory degradation.

As a near-daily smoker myself I can attest to it's lack of negative effects. I have smoked since I was 16 (which I DO NOT abdicate it's usage at that age, our brains and bodies are still developing and at that point marijuana can have a negative effect) and suffer no ills from it. My memory has showed no signs of slowing and in truth I still have a photographic memory.

I hope that I have helped clear up the truth about marijuana, and that maybe now you can see why it should be legal. Remember even it is legalized, it's not like you have to smoke it. And for those that are worried about people driving under the influence, that is and should always be illegal. Considering that tens' of thousands of people die from drunk drivers every year (and 0 from marijuana) the DWI and DUI laws need to be stronger and more enforced. Instead our police force has to waste their time punishing non-criminals for marijuana usage.

For those that are worried about it's legalization causing anarchy in the streets; look at Portugal. They have every drug legalized and there country is strong as ever. Same applies to Amsterdam, which has a lower crime right than most average US Cities. A recent poll found that nearly half of the US is pro-legalization. So for those that are against it, please get the facts and make an informed decision. Marijuana has no legit reason to be illegal and it's illegal status is a joke. Legalizing drugs is the best way to combat the "Drug War", if we take the power of drugs away from criminals and kingpins then we will win this "War." And save BILLIONS of dollars in the process (we could even make a profit of the tax revenue drugs could provide).

Stay informed!

December 4, 2009 - 4:48pm
EmpowHER Guest
Anonymous (reply to Anonymous)

sorry to correct you but in portugal the only decriminalized drug, (not legal) is marijuana. all the other drugs like heroin, cocain, lsd, mdma, etc are ilegal.
Although alot of people use it for recreative or medical purpose carrying more than 5g of marijuana can put you in jail (wish it never hapens). but i agree with all that you said and im really happy that people are informed about it and have a correct idea about the bennefits and bad things related to the use of it.
good job

February 23, 2010 - 8:14pm
Image CAPTCHA
Enter the characters shown in the image.
By submitting this form, you agree to EmpowHER's terms of service and privacy policy
Add a Comment

We value and respect our HERWriters' experiences, but everyone is different. Many of our writers are speaking from personal experience, and what's worked for them may not work for you. Their articles are not a substitute for medical advice, although we hope you can gain knowledge from their insight.

Urinary Incontinence

Get Email Updates

Health Newsletter

Receive the latest and greatest in women's health and wellness from EmpowHER - for free!