Myasthenia Gravis Treatments

Acetylcholinesterase Inhibitors

These drugs interfere with the breakdown of ACh. This increases the amount of ACh available to stimulate the muscle. These medications include:

• Pyridostigmine
• Neostigmine

Immunosuppressive Therapy

This therapy is given to suppress the immune system. As a result, there are fewer antibodies present to attack the receptors. These medications include:

• Prednisone
• Azathioprine
• Mycophenolate mofetil
• Cyclosporine
• Cyclophosphamide
• Tacrolimus

Immunoglobulin Therapy

Immunoglobulin given by IV might help reduce symptoms. The exact mechanism is unclear. This treatment seems to have fewer side effects that plasmapheresis.

Plasmapheresis

This is a procedure which cleans the blood of the abnormal antibodies. This process may need to be repeated at certain intervals.

Thymectomy

Removal of the thymus gland is recommended for most patients with MG. This surgery may improve the symptoms in some patients.

Mechanical Ventilation

This may only be needed if breathing is severely impaired. This can happen during an episode of myasthenic crisis.

Physical and Occupational Therapy

Therapy does not generally alter the course of the disease. It may be needed to help the patient cope with changes in muscle strength. It may also help with learning alternative ways to approach daily activities.