Ankylosing Spondylitis Causes & Risks

Causes

The cause of ankylosing spondylitis is not known. However, most people with ankylosing spondylitis share a common gene marker called HLA-B27. This finding indicates that genes play an important role in the development of this condition.

Risk Factors

A risk factor is something that increases your chance of getting a disease or condition.

Sex: male
Age: adolescent and young adult (ages 15-35)
Family members with ankylosing spondylitis
Having the HLA-B27 gene marker
Inflammatory bowel disease
- Ulcerative colitis
- Crohn's disease

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