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Unfortunately we cannot answer this question, as we don't know how long that flight is (over night flights can be answer from 5-10+ hours) nor any other medications you are taking which could pose a risk.October 1, 2018 - 1:19pm
Your best bet is to put call into your doctor's office where a nurse there could help you out over the phone. Also, be sure to read the recommendations on the bottle of melatonin and potential side effects.