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Have you had experience with the Wiley Protocol?

By March 3, 2009 - 11:15am
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Has anyone had experience using the Wiley Protocol of hormone replacement therapy?

It is a method where bioidentical hormones are prescribed and are given transdermally -- through the skin -- in a patent-pending cream. A primary

difference between this protocol and some others is that the hormonal levels rise and fall, similar to the way a woman's normal cycle did when she was still menstruating.

There is some controversy on the web about T.S. Wiley's qualifications for developing a medical protocol, since she is not a doctor herself, she studied anthropology (though she co-authored the book "Sex, Lies, and Menopause" with Julie Taguchi, M.D.)

Some women claim wonderful results; others claim very troubling side effects. Does anyone out there have personal experiences to share?

Add a Comment317 Comments

(reply to Anonymous)

Why don't you message me privately here on the forum and I will see what I can do to rectify whatever it is you feel has been overlooked.

Jake Raden
Wiley Systems

May 24, 2012 - 2:42pm
EmpowHER Guest

I have been lied to by so called highly educated professionals since I was 16 years old and I am now 49 years old. I have suffered with PCOS and Endometriosis since my first menstruating years. Been to dozens of so called HRT Specialists and Gynocologists. At this point I have no medical doctorette! But I can say one thing I know a heck of alot more than these so called specialists, endocronologists and researchers in the field. I have had doctors want to constantly put me on birth control, thee worst thing possible for me! They wanted to give me a hysterectomy at age 30 like my sister who is now 56 and has severe problems, mentally, emotionally and physically from not being on the right medications and hormones. I was not going to let that happen to me. I don't blame T.S. for doing what she is doing, if she feels it will help some women, then she has to do whatever it takes to get this across. I am tired of doctors trying to put me on anti- anxiety and ant-deppressants. I needed progesterone when I was younger and not one doctor prescribed it or took my blood work. They took a CBC. I asked for a CA 125 because my mother died of Ovarian Cancer, which I personally feel may have been caused by untreated Endometriosis and PCOS. The doctors ask me why I wanted that blood test, I tell them my story they don't listen. I finally found a N.D. who is a Wiley Protocal doctor and I am on my 3rd month, have lost ten pounds, no hot flashes, sleep fine and by the way almost 4 years ago I gave up and let a doctor talk me into a complete hysterectomy. I felt great for 6 months and then I packed on 30 lbs. and also by the way prior to that another doctor talked me into the pill again saying how different it was from 20 years ago, well I gained 10 lbs and another 10 lbs and grew ovarian tumors and cysts after I had worked so hard at diet and exercise in the past to keep everything under control. I tried the patch, sotto pelle (pellet) fellt the worst on the Pellet. The patch I was gaining no matter what I ate or didn't eat. The Wiley Protocol has helped me eliminate 7 lbs. of water that I could not get rid of. It has helped me lose weight and keep it off not matter what I eat or don't eat. It has stopped the gaining. I am not sure what the following month will bring but I do know that Doctors do not know everything. They talk a good talk but most of them do not know the female reproductive sytems and how important Thyroid is and are Adrenal System and Corisol levels. I have studied and doctors tell me to stay off the internet because it's confusing me, well I feel it has saved my life.
I have way more stories but I don't have time. Maybe one day I will write a book. But I think more people need to come forward to help others. So I give T.S. Kudos for coming forward and trying to help women. There are so many women who are suffering and their doctors don't offer help nor do the women know how to ask. They think it's normal. Well it's not normal to be depressed and have no energy and have severe pain 3 weeks out of the month.
I am giving the Wiley Protocol a chance and if it doesn't work for me it may work for someone. What's the worst thing that could happen, I detox myself again. But in the meantime I am feeling like I can live again

December 10, 2011 - 11:51am
EmpowHER Guest


Don't you think it's sleazy for a a guy in his 20s to be spamming women's health message boards, trying to hawk his mother's hormone products? Have you no shame?

August 26, 2011 - 12:51pm
(reply to Anonymous)

I think I've clearly and consistently identified who and what I am, with a username and complete introduction. At no point have I sought to hide in anyway my association, relationship, or occupation (I do in fact have a full-time, paid job as GM at Wiley Systems). I've also reported your post for abuse as I feel you've posted personal details that are not yours to post in public arena.

Who, might I ask, are you? Where do you work? Why do you hate the Wiley Protocol so much? For all we know, you work for someone in the same business, or who know's what. Anonymous posting that just bashes our product and our good name I think probably does more to help us than hurt us. Only someone with something to hide, does in fact, remain in the shadows.

For the record I am 29 years old, and have been a professional in the healthcare and biotechnology world since I was 23. I only went to work for Wiley Systems, my mothers company, full-time in May of 2010. I decided the traditional biotech/pharma world was full of too much marketing and sales and misinformation, and not enough helping people. The insides of big pharma are a scary, and in my opinion, dishonest place.

I'm going to ask the moderators here if maybe I could start my own Wiley Protocol thread for users to share stories and experiences like this one, and ask questions. If they agree to it, perhaps I could reach out to WP physicians and even TS Wiley herself to try and weigh in on issues and questions when they're able. I'd love to know if people are interested in that, assuming it's within the forum's rules at Empowher.com.

Best Regards,

Jake Raden
Wiley Systems, Inc.

August 26, 2011 - 10:19pm
EmpowHER Guest

I had a hysterectomy and the foolish doctor took my ovaries. I have been to 38 doctors, Mayo Clinic and Scripps trying to get some sort of normalcy back after the Hell your body goes through . It has given me lupus, fibromyalgia, fatigue, huge weight gain, horrible depression and I don't even know who this person is that they left me with. I am no where near the sweet, kind person who was always laughing. I went on the Wiley protocol cause at this stage of the game, I am about to try anything. What a mistake that was. Within the 3 months that they tell you that your receptors are good, I have gained 10 pounds, lost a significant amount of hair and it made my thyroid stop functioning and they had to double the thyroid medicine. The whole time I was on it I did not feel right and I kept calling and they said give it more time. I wouldn't recommend this at all. I do think bio identicals are great once you find the right mix for you and I thought this would work cause the lunar cycle but they really need to study this more especially on women that don't have their organs. One size does not fit all, but I hear far worse things about this than praises. Now I am back to square one but even worse.

August 25, 2011 - 8:15pm
(reply to Anonymous)

Dear Anonymous,

What a difficult journey you've been through! Normally after all the things you've been through, the only thing we see bringing relief to women in your situation is the Wiley Protocol (oophorectomy and commonly also hysterectomy) . The physicians have literally wiped out your bodies ability to produce the hormones you need to be healthy. If you are interested and willing, I'd like to offer you the opportunity to speak with one of our board physicians (who have seen collectively thousands of WP patients) about your experiences. You would be FAR from the first woman they have treated in this post-surgical state, despite what you may be thinking. The doctors I could refer your to are a board certified OB/GYN and board certified Oncologist. Trust me, they know their stuff. This is of course just an offer, and we respect any decision you make. I'm not sure if it's kosher for me to put any email addresses in this posting based on Empowher's rules, but you can always send me a private message if you would like to be put in contact with out professionals. Our number 1 priority at Wiley Protocol is happy healthy people. Treating women with advanced disease states or post-surgical endocrine disruptions such as you describe requires exceptional professional experience, not just any doctor, or even any WP trained doctor.

Best Regards,

Jake Raden
Wiley Systems, Inc.

August 25, 2011 - 9:00pm
EmpowHER Guest

At age 47 I began to put on the weight. All the symptoms of menopause were also beginning. No matter how much I worked out and ate healthy the weight would not come off. I had been on synthroid since having two bouts of radioactive iodine for graves disease. After searching I finally found a doctor who would give me a more natural thyroid med. Within three months I (easily) dropped 35 pounds.
I am in month 11 with the WP. I haven't gained any weight on it. I do have a little more belly fat than I had before but no wheres near looking pregnant. I do eat healthy most the time and take supplements.
I did have to adjust my thyroid med being on the WP. So I do believe the thyroid and WP work together. If one hormones is off it can effect the other hormones. I learn this at a local hospital hormone talk. "Hormones dance together."
I feel that starting the WP was the best decision my husband who is also on the WP and myself could of made. We feel great, look younger and act and feel like we did when we began dating 25 years ago.
So far it works for us ....

June 14, 2011 - 6:29am

I see more complaints about the Wiley Protocol have been reported on Facebook.

May 18, 2011 - 8:24am

I've been on the Wiley Protocol for 4 years now and am pretty happy with it, no more hot flashes and I have my libido back, thank goodness! I've had no health issues with it, I was hypothyroid before I went on and still am so I take Armour. Had weight problems when I hit menopause and still would have them if I quit taking my Armour or if I switch to Synthroid which I did once and immediately gained back the 20 lbs I lost. The moral of that story is that everybody's body is different so everyone will have a different reaction to meds so Wiley is not a good fit for everyone just like Synthroid isn't. As for "ANONYMOUS", I've read quite a few of her comments and she is one angry person and not only that she thinks she knows what is right for everyone, thank goodness she isn't a legislator ( I hope!). My only complaint about Wiley is the cost which is quite a bit since I'm unemployed at the moment but the alternative is feeling rotten again which happened when I went off it for a couple of months to save money. If you're on the fence about trying Wiley just do your research on doctors as who you see is critical and bear in mind that it doesn't work on everyone but if it does work it's great.

May 3, 2011 - 6:07pm
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