Estrogen is not safe for peri-menopausal or postmenopausal women. After millions of women stopped taking estrogen after the first WHI report, there were reductions in breast cancer, stroke and heart attack rates among US women, and noticeable falls in breast cancer rates in many other countries around the world. If you choose to take estrogen to reduce hot flashes, keep in mind that it affects the heart, blood vessels, brain, breasts, bones and many other organ systems and disease risks. If a doctor tells you that estrogen is safe, read the required FDA label which will educate you about what the WHI Trials really found. These are definitive data showing real risks in real human women, some of whom suffered strokes, breast cancers, heart attacks and dementia to bring you this information. Get the facts from a reliable source, and make an informed decision. The article above is biased and full of misinformation.