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I was diagnosed with recurrant major depression and have been on one antidepressant or another for over 40 years. I have also been on antipsychotics as deemed necessary by the psychiatrist. At one point it was felt I was bipolar as well, and have schizo affective disorder for which I got my disability. I was no longer able to keep working and it was well documented. It has been impossible to get off the antidepressants and maybe the reasons you site, Dr. Heller, are why. Do they add stuff to them to make them addictive? or are they just that way. I have to change meds every 2-3 years because they become ineffective and I sink into that deep dark hole that I cannot climb out of. Just a few words from the peanut gallery. bbnrse