Hi, thanks for answering! I am 60 years old, The hormones are estradial (2%) to be applied on my genitals, Estrogel (.06%) on my arm, Testim (1%) on the back of my calf - all once a day. Also 100 mg of progesterine twice a week by mouth. He diagnosed me as vestibulodynia or inflamed lubricant glands on the inside of Harts line (the urethral tissue). I have been suffering from this for 20 years and no doctor could ever find anything wrong. A biopsy was not performed. Once again thanks for the inquiry.