You wrote: "Also, no one knows the long term effects or why women have become so sick on the Wiley Protocol taking the prescribed doses. Don't blame the doctors. Don't blame the patients. Blame the Wiley regimen they are taking."
Actually, we inform every doctor who bothers to be trained by us to report adverse events to Dr. Julie Taguchi MD (Oncology/ Hematology). We absolutely keep track of everyone who does. If no one tells us what went wrong, and under what circumstances, there is no way we can possibly record it, investigate it, understand it, and make necessary changes because of it. I implore anyone who's had an adverse event on the Wiley Protocol, if you or your doctor has not reported it, to please do so as soon as possible. We can't address issues we don't know about.
And with regard to long term use and not knowing how high doses work: actually I beg to differ. We have patients we're observing who have been on the hormones for 8-9 years. In fact, some of them are cancer patients, who the medical establishment today would tell you would be the last people to survive on high dose hormone replacement. In fact we'll be publishing our clinical cancer data this year; the median time on therapy for patients is 5 years, with some stretching back much further. They've been observed for 5 years for safety and efficacy on the Wiley Protocol after standard of care treatment (chemo, radiation, surgery) for advanced cancers. The results are very interesting, but you have to wait for the full paper. We have several other IRB numbers for studies that are in progress, but it's too early to comment significantly on them yet. I promise to keep everyone posted as things evolve.
And the receptor theory is not only well known and understood by the scientists who work in the field of reproductive endocrinology, it's in textbooks on the subject. It's not conjecture, but it's application at a clinical level has never been tested until the Wiley Protocol attempted to do so. And if you want proof: post-menopausal women who take the Wiley Protocol at the correct doses (and only those women) return to pre-menopausal menstruation consistently. This is proof of everything we assert about dose dependency and receptor response. You cannot have a period with peaks of estrogen and progesterone, feel free to try it without our doses (but I don't recommend it!). If you don't understand why this represents proof, I would need to write a much longer post on the actual hormonal levels and fluctuations that occur over a normal 28 day period. However, that's all explained in depth in Sex, Lies, and Menopause, with all of the relevant sources cited for anyone to read who is interested. Again, it is well established in the scientific literature that hormones have receptors, and their methods of action vary at certain concentrations. We didn't make that up, we exploited it so women could have the option of feeling like they did when they were younger (and for some people like nanashana, even better).
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Anonymous (would be great to know who you are),
You wrote: "Also, no one knows the long term effects or why women have become so sick on the Wiley Protocol taking the prescribed doses. Don't blame the doctors. Don't blame the patients. Blame the Wiley regimen they are taking."
Actually, we inform every doctor who bothers to be trained by us to report adverse events to Dr. Julie Taguchi MD (Oncology/ Hematology). We absolutely keep track of everyone who does. If no one tells us what went wrong, and under what circumstances, there is no way we can possibly record it, investigate it, understand it, and make necessary changes because of it. I implore anyone who's had an adverse event on the Wiley Protocol, if you or your doctor has not reported it, to please do so as soon as possible. We can't address issues we don't know about.
And with regard to long term use and not knowing how high doses work: actually I beg to differ. We have patients we're observing who have been on the hormones for 8-9 years. In fact, some of them are cancer patients, who the medical establishment today would tell you would be the last people to survive on high dose hormone replacement. In fact we'll be publishing our clinical cancer data this year; the median time on therapy for patients is 5 years, with some stretching back much further. They've been observed for 5 years for safety and efficacy on the Wiley Protocol after standard of care treatment (chemo, radiation, surgery) for advanced cancers. The results are very interesting, but you have to wait for the full paper. We have several other IRB numbers for studies that are in progress, but it's too early to comment significantly on them yet. I promise to keep everyone posted as things evolve.
And the receptor theory is not only well known and understood by the scientists who work in the field of reproductive endocrinology, it's in textbooks on the subject. It's not conjecture, but it's application at a clinical level has never been tested until the Wiley Protocol attempted to do so. And if you want proof: post-menopausal women who take the Wiley Protocol at the correct doses (and only those women) return to pre-menopausal menstruation consistently. This is proof of everything we assert about dose dependency and receptor response. You cannot have a period with peaks of estrogen and progesterone, feel free to try it without our doses (but I don't recommend it!). If you don't understand why this represents proof, I would need to write a much longer post on the actual hormonal levels and fluctuations that occur over a normal 28 day period. However, that's all explained in depth in Sex, Lies, and Menopause, with all of the relevant sources cited for anyone to read who is interested. Again, it is well established in the scientific literature that hormones have receptors, and their methods of action vary at certain concentrations. We didn't make that up, we exploited it so women could have the option of feeling like they did when they were younger (and for some people like nanashana, even better).
Jake Raden
February 16, 2011 - 10:12amWiley Systems, Inc.
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