This is not a Wiley Protocol website or advocacy site. You need to address these questions with your physician. Most of the comments here are anecdotal and are not provable. It is not a good idea to ask or take prescription or instructional advice from a chat board regarding medication. Every woman has their own story, their own symptoms and their own prescriptions/dosage instructions. To know what is "new" with Wiley Protocol, you could check their website.