To stop the Wiley Protocol, you simply stop it. There are no more complicated instructions than that. If you'll be moving to a lower dose static regimen, work with your doctor perhaps to move into that regimen.
For there record, there is no science or data, peer-reviewed or published, which points to any action of the body to "store progesterone in thigh tissue". If this was a real thing, we would change the Wiley Protocol to address it. But it's not. Your body excretes exogenously applied sex steroid hormones in under 72 hours. In progesterone specifically, it even states pretty clearly, even on Wikipedia, that the half-life is 55 hours at the top-end, which is just over 2 days. See for yourself, look at the "pharmocokinetic" box: http://en.wikipedia.org/wiki/Progesterone
Without the high progesterone of the Wiley Protocol, you run a serious risk of not halting tissue growth from the estrogen which raises the specter of a lot of things going wrong in your body, from osteo-related issues to cancer. That's why we put the progesterone in there: it's not to make your life miserable, it's because it's the bio-mimetic thing to do. You need both hormones. Some physicians familiar with WP may reduce the progesterone dose slightly (-1 or -2 lines) at their discretion. I encourage any of you struggling with the luteal phase to speak with your doctor about that.
Saliva testing is mostly useful for cortisol testing. There are no established, accurate reference ranges in saliva for female sex steroid hormones and therefore we do not recommend it.
We do wish you all of the best whether you're on the WP, another BHRT regimen, or whatever your personal health choices are.
I do wish some of you would try not to badmouth a system that works for thousands of women over 10 years just because your experience wasn't perfect, or even was particularly frustrating. Were doing our best to do our part to make forward progress in the area of female health. If hormones were easy and worked predictably in everyone, they would be Over the Counter (OTC) like aspirin. But they're not and they don't. Please bear in mind, the 10,000 or so very happy patients on WP don't generally post on the internet about how happy they are, except very occasionally. If you want your experience to mean something on the Wiley Protocol for women everywhere, be it positive or negative, please send any adverse reactions with pertinent details to [email protected]. This way we can be aware of what happened, look for trends, and try to continue to improve everyday.
I try to leave this thread for patients to talk, but occasionally I feel it's warranted to step in and try to address what to us are misconceptions.
Regarding it being difficult, it is harder than taking a multivitamin, that's true. But until someone invents something that doesn't exist allowing us to slowly give hormones over time in a way that is variable and not static, the creams are the best we can do. They're far better than any other option available today for delivering the hormones with the least unintended consequences. If you're worried about carcinogenic metabolites, eating hormones as pills and trochees is the best way to generate those. Your liver and digestive system do lots of interesting things to hormones that you eat. The whole point of trans-dermal is to avoid first pass in the gut.
I see a lot of issues here that would be remedied by all of you, the patients, having better and more complete information. If you're a Wiley Protocol patient, I really want to urge you to find us on Facebook, sign up for our consumer newsletter, and/or follow T.S. Wiley's new radio show. The more informed you are, the more likely you'll find what works for you, whether it's the Wiley Protocol, or something else. Even if you're not on Wiley Protocol, we address a large range of women's health issues in all of those places, we don't just talk about WP. See for yourself.
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To stop the Wiley Protocol, you simply stop it. There are no more complicated instructions than that. If you'll be moving to a lower dose static regimen, work with your doctor perhaps to move into that regimen.
For there record, there is no science or data, peer-reviewed or published, which points to any action of the body to "store progesterone in thigh tissue". If this was a real thing, we would change the Wiley Protocol to address it. But it's not. Your body excretes exogenously applied sex steroid hormones in under 72 hours. In progesterone specifically, it even states pretty clearly, even on Wikipedia, that the half-life is 55 hours at the top-end, which is just over 2 days. See for yourself, look at the "pharmocokinetic" box: http://en.wikipedia.org/wiki/Progesterone
Without the high progesterone of the Wiley Protocol, you run a serious risk of not halting tissue growth from the estrogen which raises the specter of a lot of things going wrong in your body, from osteo-related issues to cancer. That's why we put the progesterone in there: it's not to make your life miserable, it's because it's the bio-mimetic thing to do. You need both hormones. Some physicians familiar with WP may reduce the progesterone dose slightly (-1 or -2 lines) at their discretion. I encourage any of you struggling with the luteal phase to speak with your doctor about that.
Saliva testing is mostly useful for cortisol testing. There are no established, accurate reference ranges in saliva for female sex steroid hormones and therefore we do not recommend it.
We do wish you all of the best whether you're on the WP, another BHRT regimen, or whatever your personal health choices are.
I do wish some of you would try not to badmouth a system that works for thousands of women over 10 years just because your experience wasn't perfect, or even was particularly frustrating. Were doing our best to do our part to make forward progress in the area of female health. If hormones were easy and worked predictably in everyone, they would be Over the Counter (OTC) like aspirin. But they're not and they don't. Please bear in mind, the 10,000 or so very happy patients on WP don't generally post on the internet about how happy they are, except very occasionally. If you want your experience to mean something on the Wiley Protocol for women everywhere, be it positive or negative, please send any adverse reactions with pertinent details to [email protected]. This way we can be aware of what happened, look for trends, and try to continue to improve everyday.
I try to leave this thread for patients to talk, but occasionally I feel it's warranted to step in and try to address what to us are misconceptions.
Regarding it being difficult, it is harder than taking a multivitamin, that's true. But until someone invents something that doesn't exist allowing us to slowly give hormones over time in a way that is variable and not static, the creams are the best we can do. They're far better than any other option available today for delivering the hormones with the least unintended consequences. If you're worried about carcinogenic metabolites, eating hormones as pills and trochees is the best way to generate those. Your liver and digestive system do lots of interesting things to hormones that you eat. The whole point of trans-dermal is to avoid first pass in the gut.
I see a lot of issues here that would be remedied by all of you, the patients, having better and more complete information. If you're a Wiley Protocol patient, I really want to urge you to find us on Facebook, sign up for our consumer newsletter, and/or follow T.S. Wiley's new radio show. The more informed you are, the more likely you'll find what works for you, whether it's the Wiley Protocol, or something else. Even if you're not on Wiley Protocol, we address a large range of women's health issues in all of those places, we don't just talk about WP. See for yourself.
Jake Raden
May 14, 2012 - 10:31amGeneral Manager, Wiley Systems
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