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I was prescribed this after my hyster. Unfortunately I tried *everything* else for the itch but going to my doctor who I had trusted for bladder repair, hyster and other problems. I guess I was so embarassed I don't know. Itching was relatively simple compared to what my Specialist had been thru with me! But I can tell you like many of you have said, I was MISERABLE! I could not sleep, could not walk, was irritable, cried, could not walk without pain, pain meds didn't help, ice paks, creams, powder, even my presc. meds from my surgery. Nothing! Finally I went in and got checked. 5 minutes later he says, "I know what this is" (I forget now but I am seeing if this will help my husband) and prescibes Clobetasol. The differences? I haven't had an episode in 2 years. I don't know what changed but for almost 2 months I suffered and that was too long. GIve it time ladies. If it is burning and itching and you have not been prescribed this for your vulva area, ask for it. I won't throw mine away.