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I had a hysterectomy last year and one ovary was left in tact because it was healthy and my doctor said it would provide me with some needed hormones and would decrease my mortality rate. I noticed a few months ago that my right breast (my right ovary was removed) is now significantly smaller than my left breast. They were always a bit lopsided, but now the two are noticeably different and I may need to wear some type of padding. I'm wondering if this might have something to do with the removal of the right ovary. I have no pain, no lumps, no discharge and both nipples are symetrical and identical to one another. I did read somewhere that when one breast becomes smaller than the other it could be a sign of breast cancer. I did lose about 10 pounds and I do use my right arm more now since becoming a medical assistant having to manually take blood pressures approximately 30 times a day. Is is possible it's just more noticeale now since the weight loss and my right side is leaner from the exercise? Breasts are made up mostly of fat, right?